FITC Conjugated; Anti-CD11a / LFA-1 alpha chain Monoclonal Antibody (Clone:M17/4)
Produktgrößen
0.1 mg
£551,00
30-2055-0.1MG
Über dieses Produkt
- SKU:
- 30-2055
- Zusätzliche Namen:
- Itgal||Lfa-1||Ly-15
- translate.label.attr.clone:
- M17/4
- Klonalität:
- Monoclonal
- Konjugat:
- FITC
- Weitere Details:
- CD11a (LFA-1 alpha) together with CD18 constitute leukocyte function-associated antigen 1 (LFA-1); the alphaLbeta2 integrin. CD11a is implicated in activation of LFA-1 complex. LFA-1 is expressed on the plasma membrane of leukocytes in a low-affinity conformation. Cell stimulation by chemokines or other signals leads to induction the high-affinity conformation; which supports tight binding of LFA-1 to its ligands; the intercellular adhesion molecules ICAM-1; -2; -3. LFA-1 is thus involved in interaction of various immune cells and in their tissue-specific settlement; but participates also in control of cell differentiation and proliferation and of T-cell effector functions.
- Host:
- Rat
- Immunogen:
- C57BL/6 mouse splenic secondary cytotoxic T lymphocytes
- Isotyp:
- Rat IgG2a
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg