Anti-CD2 / LFA-2 Monoclonal Antibody (Clone:LT2)-FITC Conjugated
Produktgrößen
100 tests
£581,00
30-2017-100TESTS
Über dieses Produkt
- SKU:
- 30-2017
- Zusätzliche Namen:
- T-cell surface antigen CD2; Erythrocyte receptor; T-cell surface antigen T11/Leu-5
- translate.label.attr.clone:
- LT2
- Klonalität:
- Monoclonal
- Konjugat:
- FITC
- Weitere Details:
- CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover; T cell activation induces increased CD2 expression and its lateral mobility; making easier contact between CD2 and CD58. Subsequently; T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact; thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.
- Host:
- Mouse
- Immunogen:
- Normal human blood lymphocytes.
- Isotyp:
- Mouse IgG2b
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg