APC Conjugated; Anti-CD103 / Integrin alpha E Monoclonal Antibody (Clone:Ber-ACT8)
Produktgrößen
100 tests
£620,00
30-1793-100TESTS
Über dieses Produkt
- SKU:
- 30-1793
- Zusätzliche Namen:
- ITGAE
- translate.label.attr.clone:
- Ber-ACT8
- Klonalität:
- Monoclonal
- Konjugat:
- APC
- Weitere Details:
- CD103 / Integrin alphaE is an integrin subunit that is expressed on intraepithelial lymphocytes; epithelial dendritic cells; lamina propria-derived dendritic cells; a subpopulation of lamina propria T cells; a small subset of peripheral lymphocytes; namely T reg cells; and on activated and TGF-beta stimulated lymphocytes. CD103 is in mature form cleaved into two disulfide-linked chains (C-terminal 150 kDa chain and N-terminal 25 kDa chain). It heterodimerizes with integrin beta7 subunit to form alphaE/beta7 integrin (mucosal lymphocyte 1 antigen); which through binding E-cadherin mediates homing of lymphocytes to the intestinal epithelium; and; in addition to the role in adhesion; may serve as an accessory molecule for intraepithelial lymphocyte activation.
- Host:
- Mouse
- Immunogen:
- HTLV-1 induced human T cell line MAPS16
- Isotyp:
- Mouse IgG1
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg