Anti-CD24 Monoclonal Antibody (Clone:SN3)-APC Conjugated
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100 tests
£620,00
30-1737-100TESTS
Über dieses Produkt
- SKU:
- 30-1737
- Zusätzliche Namen:
- CD24||CD24A
- translate.label.attr.clone:
- SN3
- Klonalität:
- Monoclonal
- Konjugat:
- APC
- Weitere Details:
- CD24; also known as heat-stable antigen (HSA) or nectadorin; is a small mucin-like GPI-anchored extracellular membrane glycoprotein expressed on several cell types; including B cells. When B cells are activated and induced to further maturation; however; CD24 begins to disappear. CD24 seems to act as a gate-keeper for lipid rafts; thereby regulating the activity of integrins and other proteins such as the chemokine receptor CXCR4; it is also a ligand for P-selectin. CD24 triggering induces apoptosis of B cell precursors but not in mature resting B cells; where it instead inhibits their ability to proliferate in response to activation. CD24 expression is associated with invasiveness and poorer prognosis of carcinomas and is a marker of exosomes secreted into urine and amniotic fluid.
- Host:
- Mouse
- Immunogen:
- Glycoproteins purified from human NALM-1 cell line.
- Isotyp:
- Mouse IgG1
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg