Anti-CD15 / Lewis x Blood Group antigen Monoclonal Antibody (Clone:MEM-158)-APC Conjugated
Produktgrößen
100 tests
£620,00
30-1688-100TESTS
Über dieses Produkt
- SKU:
- 30-1688
- translate.label.attr.clone:
- MEM-158
- Klonalität:
- Monoclonal
- Konjugat:
- APC
- Weitere Details:
- CD15 (Lewis X; Le(x); stage specific embryonic antigen-1; SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids; glycoproteins and proteoglycans of various cell types; e.g. granulocytes; mast cells; monocytes; macrophages; cells of gastric mucosa; nervous system or various tumour cells. There are several variants of Lewis x; such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation; based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin´s disease.
- Host:
- Mouse
- Immunogen:
- Human granulocytes
- Isotyp:
- Mouse IgM
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php