Anti-CD8a Monoclonal Antibody (Clone:53-6.7)-Low Endotoxin
Produktgrößen
0.1 mg
£482,00
30-1623-0.1MG
Über dieses Produkt
- SKU:
- 30-1623
- Zusätzliche Namen:
- Cd8a||Lyt-2||Lyt2||Ly-2|| Ly-B|| Ly-35|| Lyt-2|| BB154331
- translate.label.attr.clone:
- 53-6.7
- Klonalität:
- Monoclonal
- Weitere Details:
- The CD8a (CD8 alpha) subunit of CD8 T cell coreceptor is expressed in CD8 alpha/beta heterodimers on majority of MHC I-restricted conventional T cells and thymocytes and in CD8 alpha/alpha homodimers on subsets of memory T cells; intraepithelial lymphocytes; NK cells; macrophages and dendritic cells. Regulation of CD8 beta level on T cell surface seems to be an important mechanism to control their effector function. Assembly of CD8 alpha/beta but not alpha/alpha dimers is connected with formation or localization to the lipid rafts. Recruiting triggered TCR complexes to these membrane microdomains as well as affinity of TCR to MHC I is modulated by CD8; thereby affecting the functional diversity of the TCR signaling.
- Format:
- Low Endotoxin
- Host:
- Rat
- Immunogen:
- Mouse spleen cells
- Isotyp:
- Rat IgG2a
- Aufreinigung:
- Purified by protein-G affinity chromatography
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php