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Antikörper

Anti-TPX2 Monoclonal Antibody (Clone:TPX2-01)

Produktgrößen
0.1 mg
£570,00
30-1585-0.1MG
Über dieses Produkt
SKU:
30-1585
Zusätzliche Namen:
TPX2||C20orf1||C20orf2||DIL2||HCA519
translate.label.attr.clone:
TPX2-01
Klonalität:
Monoclonal
Weitere Details:
TPX2 is a microtubule-associated protein; which is a critical regulator of mitosis. At the beginning of mitosis; TPX2 is released and plays a significant role in mitotic spindle formation and subsequent proper segregation of chromosomes during cell division. After completion of mitosis the TPX2 protein disappears; but has also role in DNA damage response. Its overexpression has been demonstrated in many types of carcinomas. TPX2 belongs to the markers of worse tumor prognosis. On the other hand; down-regulation of TPX2 can inhibit cancer cell proliferation; migration and invasion.
Format:
Purified
Host:
Mouse
Immunogen:
Human TPX2
Isotyp:
Mouse IgG1
Aufreinigung:
Purified from hybridoma culture supernatant by protein-A affinity chromatography.
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at 2-8[o]C. Do not freeze.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody
  • Datenblatt des Herstellers:1.jpg
Figure 2: Immunoprecipitation of TPX2 from nuclear extract of HEK293 cells using monoclonal antibody TPX2-01. 1) nuclear extract; 2) antibody; 3) immunoprecipitate; 4) carrier
Figure 3: Immunocytochemistry of TPX2 using monoclonal antibody TPX2-01 in glioblastoma cell line T98G: a) interphase; b) mitosis. c) Immunohistochemistry of TPX2 in U87MG human glioblastoma cells (orthotopic xenograft in murine brain). Bar: 20 µm.
Figure 3: Immunocytochemistry of TPX2 using monoclonal antibody TPX2-01 in glioblastoma cell line T98G: a) interphase; b) mitosis. c) Immunohistochemistry of TPX2 in U87MG human glioblastoma cells (orthotopic xenograft in murine brain). Bar: 20 µm.