Anti-CD169 / Siglec-1 Monoclonal Antibody (Clone:7-239)
Produktgrößen
0.1 mg
£532,00
30-1575-0.1MG
Über dieses Produkt
- SKU:
- 30-1575
- Zusätzliche Namen:
- SIGLEC1||SN
- translate.label.attr.clone:
- 7-239
- Klonalität:
- Monoclonal
- Weitere Details:
- CD169; also known as Siglec-1 or sialoadhesin; is a type I transmembrane glycoprotein of the sialic acid binding Ig-like lectin family. It binds to sialylated glycoproteins on various haematopoietic cells to mediate cell-cell interactions. CD169 is expressed on a subset of macrophages and dendritic cells. On CD14+ monocytes its expression can be induced by interferon alpha and gamma. High expression of CD169 is observed in the spleen; lymph nodes; bone marrow; and under inflammatory conditions rheumatoid arthritis and atherosclerosis; lower in the liver; lungs and gut. It has been shown to be involved in antigen presentation to invariant NKT cells; which play an important role in the innate arm of the immune system to modulate the subsequent acquired immune responses.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- human rhinovirus 14-infected monocyte-derived dendritic cells
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- Purified by protein-A affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php