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Antikörper

Anti-Myeloperoxidase (MPO) Monoclonal Antibody (Clone:MPO421-8B2)

Produktgrößen
0.1 mg
£570,00
30-1572-0.1MG
Über dieses Produkt
SKU:
30-1572
Zusätzliche Namen:
MPO
translate.label.attr.clone:
MPO421-8B2
Klonalität:
Monoclonal
Weitere Details:
Myeloperoxidase (MPO) is a heme enzyme that is localized in azurophilic (primary) granules of myeloid cells and its synthesis occurs at an early stage of differentiation. The mature myeloperoxidase is a tetramer composed of two light (12 kDa) and two heavy (60 kDa) chains. This enzyme uses hydrogen peroxide to oxidize numerous substrates; including serotonin; melatonin or chloride; to produce reactive free radicals that contribute to immune reactions of myeloid cells against pathogens. Myeloperoxidase functions not only in host defense by mediating efficient microbial killing but also can contribute to progressive tissue damage in chronic inflammatory states such as atherosclerosis or acute pancreatitis.
Format:
Purified
Host:
Mouse
Immunogen:
Human myeloperoxidase
Isotyp:
Mouse IgG1
Aufreinigung:
Purified by protein-A affinity chromatography
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at 2-8[o]C. Do not freeze.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody