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Antikörper

APC Conjugated Anti-CD154 / CD40L Monoclonal Antibody (Clone: 24-31)

Produktgrößen
100 Tests
£620,00
30-1564AC-100TESTS
Über dieses Produkt
SKU:
30-1564AC
Zusätzliche Namen:
CD40LG||CD40L||TNFSF5||TRAP
translate.label.attr.clone:
24-31
Klonalität:
Monoclonal
Konjugat:
APC
Weitere Details:
CD154 / CD40L (CD40 ligand) is a member of the tumor necrosis factor family; and is expressed primarily on activated CD4+ lymphocytes; but also on mast cells; basophils; eosinophils and human dendritic cells. Its counter-receptor CD40 is expressed on antigen presenting cells; including dendritic cells; macrophages; and B cells; and also on fibroblasts. Triggering of CD40 by CD40L causes maturation of dendritic cells and upregulation of antigen presentation in functions of the MHC and costimulatory molecules. CD40L also functions as a direct stimulating factor for T cells. CD40L plays also roles e.g. in antibody class switching and modulation of apoptosis in the germinal center.
Format:
Purified
Host:
Mouse
Immunogen:
human CD154 fusion protein
Isotyp:
Mouse IgG1
Aufreinigung:
Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at 2-8[o]C protected from light. Do not freeze.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody
Figure 2: Flow cytometry multicolor surface staining pattern of human lymphocytes using anti-human CD154 (24-31) APC antibody (10 μl reagent per million cells in 100 μl of cell suspension) and anti-human CD3 (UCHT1) PE antibody (20 μl reagent per million cells in 100 μl of cell suspension).
Figure 3: Separation of human lymphocytes (red-filled) from blood debris (black-dashed) in flow cytometry analysis (surface staining) of human stimulated (PHA + ionomycin) peripheral blood mononuclear cells stained using anti-human CD154 (24-31) APC antibody (10 μl reagent per million cells in 100 μl of cell suspension).
Figure 3: Separation of human lymphocytes (red-filled) from blood debris (black-dashed) in flow cytometry analysis (surface staining) of human stimulated (PHA + ionomycin) peripheral blood mononuclear cells stained using anti-human CD154 (24-31) APC antibody (10 μl reagent per million cells in 100 μl of cell suspension).