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Antikörper

Anti-CD154 / CD40L Monoclonal Antibody (Clone: 24-31) Purified

Produktgrößen
0.1 mg
£532,00
30-1564-0.1MG
Über dieses Produkt
SKU:
30-1564
Zusätzliche Namen:
CD40LG||CD40L||TNFSF5||TRAP
translate.label.attr.clone:
24-31
Klonalität:
Monoclonal
Weitere Details:
CD154 / CD40L (CD40 ligand) is a member of the tumor necrosis factor family; and is expressed primarily on activated CD4+ lymphocytes; but also on mast cells; basophils; eosinophils and human dendritic cells. Its counter-receptor CD40 is expressed on antigen presenting cells; including dendritic cells; macrophages; and B cells; and also on fibroblasts. Triggering of CD40 by CD40L causes maturation of dendritic cells and upregulation of antigen presentation in functions of the MHC and costimulatory molecules. CD40L also functions as a direct stimulating factor for T cells. CD40L plays also roles e.g. in antibody class switching and modulation of apoptosis in the germinal center.
Format:
Purified
Host:
Mouse
Immunogen:
human CD154 fusion protein
Isotyp:
Mouse IgG1
Aufreinigung:
Purified by protein-A affinity chromatography
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at 2-8[o]C. Do not freeze.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody
Figure 2: Separation of human CD154 positive cells (red-filled) from CD154 negative cells (black-dashed) in flow cytometry analysis (surface staining) of stimulated (PMA + ionomycin) peripheral blood mononuclear cells stained using anti-human CD154 (24-31) purified antibody GAM APC.
Figure 2: Separation of human CD154 positive cells (red-filled) from CD154 negative cells (black-dashed) in flow cytometry analysis (surface staining) of stimulated (PMA + ionomycin) peripheral blood mononuclear cells stained using anti-human CD154 (24-31) purified antibody GAM APC.