Anti-CD243 / MDR-1 Monoclonal Antibody (Clone:UIC2)
Produktgrößen
0.1 mg
£532,00
30-1552-0.1MG
Über dieses Produkt
- SKU:
- 30-1552
- Zusätzliche Namen:
- ABCB1||MDR1||PGY1
- translate.label.attr.clone:
- UIC2
- Klonalität:
- Monoclonal
- Weitere Details:
- CD243; also known as multidrug resistant protein 1 (MDR-1) or P-glycoprotein (Pgp) is an ATP binding cassette (ABC)-containing efflux transporter for xenobiotic lipophilic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. It is expressed in many tissues; including the brain; liver; pancreas; testes; kidney; and blood (B; T; NK cells; but not monocytes).
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- NIH 3T3 cells transfected with human CD243 (MDR-1) cDNA
- Isotyp:
- Mouse IgG2a
- Aufreinigung:
- Purified by protein-A affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php