APC Conjugated Anti-Human CD266 Monoclonal Antibody (Clone: ITEM-4)
Produktgrößen
0.1 mg
£620,00
30-1545AC-0.1MG
Über dieses Produkt
- SKU:
- 30-1545AC
- Zusätzliche Namen:
- TNF receptor superfamily member 12A; TWEAKR; FN14; TNFRSF12A
- translate.label.attr.clone:
- ITEM-4
- Klonalität:
- Monoclonal
- Konjugat:
- APC
- Weitere Details:
- CD266 / TWEAK R (TNFRSF12A); also known as FN14 (fibroblast growth factor-inducible 14) is a receptor for CD255 / TWEAK; the TNF-like weak inducer of apoptosis. CD266 is expressed on endothelial cells; as well as on some cancer tissues; and plays a role in CD255-induced endothelial cell migration; proliferation; and angiogenesis. The CD255-CD266 interaction; or antibody-mediated triggering of CD266 is also able to induce apoptosis and necrosis in CD266-positive cells (including tumor cells); which might have therapeutic potential. Specificity: The mouse monoclonal antibody ITEM-4 recognizes an extracellular epitope of CD266 / TWEAK R; a TNFR superfamily receptor for CD255 / TWEAK; a TNF-like weak inducer of apoptosis.
- Host:
- Mouse
- Immunogen:
- Human CD266-transfected P815 cells
- Isotyp:
- Mouse IgG2b
- Aufreinigung:
- Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Protect from prolonged exposure to light. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg