Anti-CD32 / FcgammaRII Monoclonal Antibody (Clone:3D3)
Produktgrößen
0.1 mg
£532,00
30-1541-0.1MG
Über dieses Produkt
- SKU:
- 30-1541
- Zusätzliche Namen:
- FCGR2B||CD32||FCG2||IGFR2
- translate.label.attr.clone:
- 3D3
- Klonalität:
- Monoclonal
- Weitere Details:
- CD32 (FcgammaRII) is a low affinity receptor for aggregated IgG. It is strongly expressed on monocytes; granulocytes; myeloid and myeloblastic cell lines; and weakly on B cells; CD34+ bone marrow cells; and resting and activated platelets. After binding its ligand; CD32 induces IgG-mediated phagocytosis and oxidative burst in monocytes and neutrophils; whereas in B cells it mediates a negative signal. This polymorphic transmembrane glycoprotein is expressed not only in the activating (CD32a) and inhibitory isoform (CD32b); but also in individual variants with differing avidities for IgG subtypes (e.g. the CD32a131R and CD32a131H allotypes).
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- purified glycosylated recombinant human FcgammaRIIa2
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- Purified by protein-A affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg