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Antikörper

Anti-CD2 Monoclonal Antibody (Clone:TS1/8)

Produktgrößen
0.1 mg
£532,00
30-1536-0.1MG
Über dieses Produkt
SKU:
30-1536
Zusätzliche Namen:
T-cell surface antigen CD2; Erythrocyte receptor; T-cell surface antigen T11/Leu-5
translate.label.attr.clone:
TS1/8
Klonalität:
Monoclonal
Weitere Details:
CD2 (also known as LFA-2) belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover; T cell activation induces increased CD2 expression and its lateral mobility; making easier contact between CD2 and CD58. Subsequently; T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact; thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.
Format:
Purified
Host:
Mouse
Immunogen:
Cytotoxic T lymphocytes
Isotyp:
Mouse IgG1
Aufreinigung:
Purified by protein-A affinity chromatography
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at 2-8[o]C. Do not freeze.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody