APC Conjugated Anti-CD88 / C5aR Monoclonal Antibody (Clone:S5/1)
Produktgrößen
100 tests
£649,00
30-1531AC-100TESTS
Über dieses Produkt
- SKU:
- 30-1531AC
- Zusätzliche Namen:
- C5AR1||C5AR||C5R1
- translate.label.attr.clone:
- S5/1
- Klonalität:
- Monoclonal
- Konjugat:
- APC
- Weitere Details:
- CD88 / C5aR is a G protein-coupled seven membrane-spanning protein serving as a receptor for C5a component of the complement cascade; and is expressed mainly by monocytes; macrophages; neutrophils; eosinophils; and mast cells; but also e.g. by hepatocytes; glial cells; vascular endothelial cells; or cardiomyocytes. The binding of C5a to CD88 is associated with inflammatory response; including superoxide anion production; chemotaxis; and increased production of acute phase proteins. Expression of CD88 on synovial mast cells and their C5a-mediated degranulation plays a role in pathogenesis of rheumatoid arthritis.
- Host:
- Mouse
- Immunogen:
- Recombinant N-terminal peptide (Asp15-Asp27) of human C5aR
- Isotyp:
- Mouse IgG2a
- Aufreinigung:
- Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:30-1531AC 1.jpeg
