Anti-CD42a Monoclonal Antibody (Clone:GR-P)
Produktgrößen
0.1 mg
£532,00
30-1529-0.1MG
Über dieses Produkt
- SKU:
- 30-1529
- Zusätzliche Namen:
- GP9
- translate.label.attr.clone:
- GR-P
- Klonalität:
- Monoclonal
- Weitere Details:
- CD42a; also known as Glycoprotein 9 (GPIX); composes together with GPIb alpha; GPIb beta and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury; as well as to thrombin; coagulation factors XI and XII; high molecular wight kininogen; TSP-1; integrin Mac-1 and P-selectin. Defects in the gene encoding CD42a are a cause of Bernard-Soulier syndrome; also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Human acute lymphoblastic leukemia cells
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- Purified by protein-A affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php