Anti-CD42a Monoclonal Antibody (Clone:GR-P) PE-Cy™7 Conjugated
Produktgrößen
100TESTS
£760,00
30-1529-PE-Cy7-100TESTS
Über dieses Produkt
- SKU:
- 30-1529-PE-Cy7
- Zusätzliche Namen:
- GP9
- translate.label.attr.clone:
- GR-P
- Klonalität:
- Monoclonal
- Weitere Details:
- Specificity: The mouse monoclonal antibody GR-P (also known as GRP-P) recognizes an extracellular epitope of CD42a (glycoprotein 9); a 22 kDa transmembrane protein constitutively expressed on megakaryocytes and platelets. Description: CD42a; also known as Glycoprotein 9 (GPIX); composes together with GPIb alpha; GPIb beta and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury; as well as to thrombin; coagulation factors XI and XII; high molecular wight kininogen; TSP-1; integrin Mac-1 and P-selectin. Defects in the gene encoding CD42a are a cause of Bernard-Soulier syndrome; also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Human acute lymphoblastic leukemia cells
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- Purified antibody is conjugated with activated tandem dye of R-phycoerythrin-cyanine 7 (PE-Cy™7) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Protect from prolonged exposure to light. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:Image 1.jpg
