APC Conjugated Anti-DLL4 (Clone : MHD4-46)
Produktgrößen
0.1 mg
£649,00
30-1517AC-0.1MG
Über dieses Produkt
- SKU:
- 30-1517AC
- Zusätzliche Namen:
- Delta like ligand 4; AOS6; canonical Notch ligand 4;delta like canonical Notch ligand 4
- translate.label.attr.clone:
- MHD4-46
- Klonalität:
- Monoclonal
- Konjugat:
- APC
- Weitere Details:
- DLL4 (Delta-like 4) is one of five ligands of Notch receptors. It interacts with Notch1 and Notch4. DLL4 is up-regulated at sites of physiologic and pathologic angiogenesis; whereas its expression is low in most adult normal tissues. It is also highly expressed in human clear-cell renal carcinomas; bladder cancers; and breast cancers. Blocking the DLL4-Notch interaction seems to be a promissing therapeutic approach. Specificity : The mouse monoclonal antibody MHD4-46 recognizes the extracellular domain of DLL4 (Delta-like ligand 4); a type I transmembrane protein which plays an important role in vascular development.
- Immunogen:
- recombinant soluble human DLL4
- Isotyp:
- Mouse IgG1 kappa
- Aufreinigung:
- Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Conjugated Protein
- Datenblatt des Herstellers:30-1517AC 1.jpeg