Anti-LARGE1 Monoclonal Antibody (Clone:LARGE-02)
Produktgrößen
0.1 mg
£581,00
30-1504-0.1MG
Über dieses Produkt
- SKU:
- 30-1504
- Zusätzliche Namen:
- LARGE1||KIAA0609||LARGE
- translate.label.attr.clone:
- LARGE-02
- Klonalität:
- Monoclonal
- Weitere Details:
- LARGE1 serves as a glycosyltransferase which participates in glycosylation of the muscle membrane protein alpha-dystroglycan. Mutations of LARGE1 lead to hypoglycosylation of alpha-dystroglycan and cause congenital muscular dystrophy (MDC1D) associated with severe mental retardation. Altered alpha-dystroglycan glycosylation may also play a role in cancer; as hypoglycosylation of the protein and loss of laminin binding have been demonstrated in invasive carcinoma cells.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human LARGE1 (amino acids 35-142)
- Isotyp:
- Mouse IgG2b
- Aufreinigung:
- Purified by protein-A affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg