Anti-CD148 Monoclonal Antibody (Clone:MEM-CD148/05)
Produktgrößen
0.1 mg
£532,00
30-1499-0.1MG
Über dieses Produkt
- SKU:
- 30-1499
- Zusätzliche Namen:
- PTPRJ||DEP1
- translate.label.attr.clone:
- MEM-CD148/05
- Klonalität:
- Monoclonal
- Weitere Details:
- CD148 (also known as HPTP-eta or DEP-1) is a transmembrane protein tyrosin phosphatase containing eight fibronectin type III extracellular domains. This protein is known to inhibit transduction of mitogenic signals in non-hematopoietic cells (fibroblasts; epithelial cells); and signal transduction downstream of T cell receptor; however; it also augments immunoreceptor signaling in B cells and macrophages via dephosphorylating C-terminal tyrosine of Src-family tyrosine kinases. CD148 expression increases after in vitro activation of peripheral blood leucocytes. It can be also used as marker of the most mature human thymocytes; and leukemic cells corresponding to this stadium of thymocyte differentiation. In contrast; in mice the CD148 expression sharply drops through the double positive stage to the single positive thymocytes.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Human recombinant CD148 (amino acids 1-444)
- Isotyp:
- Mouse IgG2b
- Aufreinigung:
- Purified by protein-A affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php