Anti-Drebrin Monoclonal Antibody (Clone:DBN-N-03)
Produktgrößen
0.1 mg
£581,00
30-1496-0.1MG
Über dieses Produkt
- SKU:
- 30-1496
- Zusätzliche Namen:
- Developmentally-regulated brain protein
- translate.label.attr.clone:
- DBN-N-03
- Klonalität:
- Monoclonal
- Weitere Details:
- Drebrin is an actin-binding protein; which is expressed mainly in neurons and plays important role in their morphogenesis. The highest level of its expression is in developing brain. Both in neurons and non-neuronal cells drebrin acts as a key regulator of actin cytoskeleton remodelling; affecting especially intercellular junctions; such as dendritic spines of neurons or the immune synapses of T cells. Decrease of drebrin amount in the brain seems to be associated with Alzheimer's disease and Down syndrome; and in case of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) lower drebrin expression correlates with higher risk of relapse.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Bacterially expressed N-terminal fragment of recombinant human drebrin (aa 1-326)
- Isotyp:
- Mouse IgG2b
- Aufreinigung:
- Purified by protein-A affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg
