Anti-Notch 1 Monoclonal Antibody (Clone:mN1A)
Produktgrößen
0.1 mg
£532,00
30-1459-0.1MG
Über dieses Produkt
- SKU:
- 30-1459
- Zusätzliche Namen:
- NOTCH1; TAN1; Motch A; mT14; p300
- translate.label.attr.clone:
- mN1A
- Klonalität:
- Monoclonal
- Weitere Details:
- Notch 1 is a 270-300 kDa transmembrane heterodimeric protein with multiple extracellular growth factor-like repeats; and with an intracellular domain consisting of multiple different domain types. It serves as a receptor for membrane ligands; such as Delta 1; Jagged1 (CD339); and Jagged2; and regulates cell fate decisions. Upon ligand binding the transmembrane form of Notch 1 is repeatedly cleaved to provide approximately 120 kDa Notch intracellular fragment (NICD); which translocates to the nucleus and acts as a part of transcriptional complexes that alter differentiation; proliferation; and apoptosis. The highest level of Notch 1 expression is in brain; lung and thymus.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- GST fusion protein containing cdc10-NCR region of mouse Notch1
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- Purified by protein-A affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg