Anti-CD314 Monoclonal Antibody (Clone:1D11)
Produktgrößen
0.1 mg
£532,00
30-1458-0.1MG
Über dieses Produkt
- SKU:
- 30-1458
- Zusätzliche Namen:
- KLRK1||D12S2489E||NKG2D
- translate.label.attr.clone:
- 1D11
- Klonalität:
- Monoclonal
- Weitere Details:
- CD314; also known as NKG2D (natural killer receptor G2D) or KLRK1 (killer cell lectin-like receptor subfamily K; member 1); is a homodimeric C-type lectin-like activating receptor and costimulator with type II membrane orientation (C teminus extracellular). CD314 homodimers are associated with DAP10; a membrane adaptor protein that signals similar to CD28 by recruitment of phosphatidylinositol 3-kinase. Engagement of CD314 amplifies antigen-specific T cell responses in CD314-positive T cell populations. In NK cells; CD314 is a primary activating receptor. As CD314 ligands the MHC class-I chain-related proteins A and B (MICA; MICB) and UL16-binding proteins (ULBPs) have been identified.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- NKL cell line
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- Purified by protein-A affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php