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Antikörper

Anti-CD16 / FcgammaRIII Monoclonal Antibody (Clone:3G8)

Produktgrößen
0.1 mg
£532,00
30-1454-0.1MG
Über dieses Produkt
SKU:
30-1454
Zusätzliche Namen:
FCGR3A||CD16A||FCG3||FCGR3||IGFR3
translate.label.attr.clone:
3G8
Klonalität:
Monoclonal
Weitere Details:
CD16 (FcgammaRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgammaRIII is expressed in two forms - FcgammaRIII-A and -B. FcgammaRIII-A is a transmembrane protein of monocytes; macrophages; NK cells and a subset of T cells. It is associated with FcepsilonRI-gamma subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcgammaRIII-A is associated; moreover; with FcepsilonRI-beta subunit. Besides IgG; FcgammaRIII-A can be triggered also by oligomeric IgE. FcgammaRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.
Format:
Purified
Host:
Mouse
Immunogen:
Human neutrophils
Isotyp:
Mouse IgG1
Aufreinigung:
Purified by protein-A affinity chromatography
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at 2-8[o]C. Do not freeze.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody
  • Datenblatt des Herstellers:1.jpg
Figure 2: Expression profiling on peripheral blood subsets using anti-human CD16 purified antibody (clone 3G8). HCDM CDMaps standardized procedures (Kuzilkova D et al. Front Immunol. 2022;13:827898) were used for cell isolation and surface staining of blood leukocytes; with the modification of staining protocol using cytometry test tubes. Suspension of blood leukocytes isolated from buffy coats (2 x 106 cells) with residual erythrocytes lysed with 10X diluted EXCELLYSE Live solution (#ED706
Figure 3: Anti-human CD16 purified antibody (clone 3G8) works in flow cytometry application. Analysis of the antibody staining profile was performed on blood leukocytes isolated from buffy coats. HCDM CDMaps standardized procedures (Kuzilkova D et al. Front Immunol. 2022;13:827898) were used for cell isolation and surface staining of blood leukocytes; with the modification of staining protocol using cytometry test tubes. Mouse monoclonal anti-human CD16 purified antibody (clone 3G8) was used
Figure 4: Separation of human CD16 positive lymphocytes (red-filled) from CD16 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of peripheral whole blood stained using anti-human CD16 (3G8) purified antibody (concentration in sample 2 μg/ml; GAM APC).
Figure 4: Separation of human CD16 positive lymphocytes (red-filled) from CD16 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of peripheral whole blood stained using anti-human CD16 (3G8) purified antibody (concentration in sample 2 μg/ml; GAM APC).