Anti-CD64 / FcgammaRI Monoclonal Antibody (Clone:10.1)
Produktgrößen
0.1 mg
£532,00
30-1452-0.1MG
Über dieses Produkt
- SKU:
- 30-1452
- Zusätzliche Namen:
- FCGR1A||FCG1||FCGR1||IGFR1
- Klonalität:
- Monoclonal
- Weitere Details:
- CD64 (FcgammaRI) is a cell surface receptor for Fc region of IgG. It is composed of specific ligand binding alpha subunit and promiscuous gamma subunit; which is indispensable for tyrosine-based signaling. However; even the alpha subunit can transduce signals leading to cellular effector functions. The isoform FcgammaRIa1 binds human IgG with high affinity; has limited myeloid cell distribution; and a relatively large intracellular domain. Products of related genes include FcgammaRIb and FcgammaRIc isoforms; but these specify low affinity IgG receptors if functionally expressed at all. Besides a role in antigen clearance; FcgammaRI (a1) can potently enhance MHC class I and II antigen presentation in vitro and in vivo.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Rheumatoid synovial fluid cells and fibronectin purified human monocytes
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- Purified by protein-A affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php