Anti-Granzyme B Monoclonal Antibody (Clone:CLB-GB11)
Produktgrößen
0.1 mg
£570,00
30-1444-0.1MG
Über dieses Produkt
- SKU:
- 30-1444
- Zusätzliche Namen:
- GZMB||CGL1||CSPB||CTLA1||GRB
- translate.label.attr.clone:
- CLB-GB11
- Klonalität:
- Monoclonal
- Weitere Details:
- Granzyme B is a serine protease that is expressed in cytoplasmic granules of cytotoxic T lymphocytes and NK cells. Vectorial secretion of perforin and granzymes is responsible for their granule-mediated cytotoxicity. Granzyme B plays a pivotal role in the induction of apoptosis in the target cells by activation of caspases. Moreover; granzyme B was reported to cleave directly alpha-tubulin; leading to perturbation of microtubule networks during the induced cell death.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Human NK cell line YT-INDY-derived granzyme B
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- Purified by protein-A affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php