Anti-ABRA1 Monoclonal Antibody (Clone:ABRA1-01)
Produktgrößen
0.1 mg
£581,00
30-1431-0.1MG
Über dieses Produkt
- SKU:
- 30-1431
- Zusätzliche Namen:
- ABRAXAS1||ABRA1||CCDC98||FAM175A||UNQ496/PRO1013
- translate.label.attr.clone:
- ABRA1-01
- Klonalität:
- Monoclonal
- Weitere Details:
- ABRA1 (Abraxas); also known as CCDC98; is an adaptor protein that is essential for formation and function of BRCA1 A tumor suppressor complex. This complex plays critical roles in DNA repair; cell cycle checkpoint control; and maintenance of genomic stability. ABRA1 mediates interaction of ubiquitin-interacting motif-containing protein RAP80 and deubiquitination enzyme BRCC36 with BRCA1/BARD1. ABRA1 controls both DNA-damage-induced formation of BRCA1 foci and BRCA1-dependent G2/M checkpoint activation.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to amino acids 1-313 of ABRA1 with N-terminal His6 tag
- Isotyp:
- Mouse IgG
- Aufreinigung:
- Purified by protein-A affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg