Anti-H-Ras Monoclonal Antibody (Clone:H-RAS-03)
Produktgrößen
0.1 mg
£551,00
30-1365-0.1MG
Über dieses Produkt
- SKU:
- 30-1365
- Zusätzliche Namen:
- HRAS||HRAS1
- translate.label.attr.clone:
- H-RAS-03
- Klonalität:
- Monoclonal
- Weitere Details:
- H-Ras is one of three ubiquitously isoforms of Ras GTPase that operate at the intracellular leaflet of the plasma membrane to regulate multiple signal transduction pathways; such as mitogen-activated protein kinase (MAPK) cascade. H Ras is anchored to the plasma membrane by farnesyl and two palmityl residues. GTP loading decreases H-Ras affinity for lipid rafts and allows the protein to target to nonraft microdomains; the primary sites of H-Ras signaling. Sos protein and other guanine nucleotide-exchange factors catalyze dissociation of GDP from Ras. Besides its roles in the plasma membrane; active H-Ras also diffuses through the cytoplasm on nanoparticles termed rasosomes; which is dependent on Ras palmitoylation.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Peptide corresponding to amino acids DIHQYREQIKRVKDSDDC of human H-Ras protein
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- Purified by protein-A affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg