Anti-SHIP-1 Monoclonal Antibody (Clone:SHIP-01)
Produktgrößen
0.1 mg
£551,00
30-1362-0.1MG
Über dieses Produkt
- SKU:
- 30-1362
- Zusätzliche Namen:
- INPP5D||SHIP||SHIP1
- translate.label.attr.clone:
- SHIP-01
- Klonalität:
- Monoclonal
- Weitere Details:
- SHIP-1 (SH2 domain containing inositol phosphatase-1) is a 5´inositol phosphatase that regulates cell responses in lymphocytes and myeloid cells by hydrolyzing the second messenger PI(3;4;5) trisphosphate. SHIP-1 is recruited upon engagement of both inhibitory and activatory receptors; such as FcgammaRIIB; Fcgamma RIII; FcepsilonRI or cytokine and growth factor receptors; and supresses PI3K-dependent signaling; down-regulates cell migration and invasion of transformed cells and phagocytosis. SHIP-1 also serves as a scaffold for the recruitment of other proteins to the plasma membrane.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Peptide coresponding to a sequence within N-terminal domain of Human SHIP-1.
- Isotyp:
- Mouse IgG2a
- Aufreinigung:
- Purified by protein-A affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg