Anti-Daxx / DAP6 Monoclonal Antibody (Clone:DAXX-03)
Produktgrößen
0.1 mg
£551,00
30-1359-0.1MG
Über dieses Produkt
- SKU:
- 30-1359
- Zusätzliche Namen:
- DAXX||BING2||DAP6
- translate.label.attr.clone:
- DAXX-03
- Klonalität:
- Monoclonal
- Weitere Details:
- Daxx is an apoptosis-modulating death-domain associated protein with functions in transcriptional regulation. Daxx functions bot in cytoplasm; where it interacts with Fas; and in nucleus (residing in PML oncogenic domains); where it is involved in SUMO-dependent regulation of transcription and subnuclear compartmentalization. Daxx senzitizes the cells to apoptosis; but on the other hand; this protein may also serve in preventing apoptosis in the early embryo. Even regarding the transcription; Daxx can serve both as a corepressor and a coactivator. During ischemic stress; Daxx translocates from the nucleus to the cytoplasm; where in regulates sodium hydrogen exchanger isoform 1 (NHE1).
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- His6-tagged protein corresponding to amino acids 580-740 of human Daxx.
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- Purified by protein-A affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg