Anti-CD24 Monoclonal Antibody (Clone:SN3) PE-Cy™5 conjugated
Produktgrößen
100TESTS
£724,00
30-1353PE-Cy5-100TESTS
Über dieses Produkt
- SKU:
- 30-1353PE-Cy5
- Zusätzliche Namen:
- CD24||CD24A||HSA||nectadorin||SCLC4
- translate.label.attr.clone:
- SN3
- Klonalität:
- Monoclonal
- Konjugat:
- R-PE/CY5
- Weitere Details:
- Specificity: The antibody SN3 reacts with CD24; a 35-45 kDa heavily glycosylated cell surface antigen. CD24 is expressed by granulocytes; B lymphocytes and by some activated T cells and T cell malignancies. It is not expressed on human thymocytes. Description: CD24; also known as heat-stable antigen (HSA) or nectadorin; is a small mucin-like GPI-anchored extracellular membrane glycoprotein expressed on several cell types; including B cells. When B cells are activated and induced to further maturation; however; CD24 begins to disappear. CD24 seems to act as a gate-keeper for lipid rafts; thereby regulating the activity of integrins and other proteins such as the chemokine receptor CXCR4; it is also a ligand for P-selectin. CD24 triggering induces apoptosis of B cell precursors but not in mature resting B cells; where it instead inhibits their ability to proliferate in response to activation. CD24 expression is associated with invasiveness and poorer prognosis of carcinomas and is a marker of exosomes secreted into urine and amniotic fluid.
- Host:
- Mouse
- Immunogen:
- Glycoproteins purified from human NALM-1 cell line.
- Isotyp:
- Mouse IgG1 kappa
- Aufreinigung:
- Purified antibody is conjugated with activated tandem dye of R-phycoerythrin-cyanine 5 (PE-Cy™5) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:img1.jpg
