Anti-LIME Monoclonal Antibody (Clone:LIME-10)
Produktgrößen
0.1 mg
£581,00
30-1274-0.1MG
Über dieses Produkt
- SKU:
- 30-1274
- Zusätzliche Namen:
- LIME1||LIME||LP8067
- translate.label.attr.clone:
- LIME-10
- Klonalität:
- Monoclonal
- Weitere Details:
- LIME (Lck-interacting molecule) is a 30 kDa double-palmitoylated protein with unusually basic cytoplasmic domain; expressed by T cells. After ligation of CD4 or CD8 T cell coreceptors; LIME is phosphorylated by Src-family kinases and associates with Lck and Fyn kinases and with their negative regulator Csk. Interestingly; Csk-mediated phosphorylation of C-terminal negative-regulatory tyrosine of LIME-associated Lck can result in increase of enzymatic activity compared with the total pool of Lck; thus; LIME serves as a positive regulator of TCR-dependent T cell signaling. However; under some circumstances; LIME may mediate inhibitory signals.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- COOH-terminal peptide comprising residues 281-296 of the human LIME conjugated to keyhole limpet hemocyanin.
- Isotyp:
- Mouse IgG2a
- Aufreinigung:
- Purified by protein-A affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg