Anti-CD33 Monoclonal Antibody (Clone:HIM3-4)
Produktgrößen
0.1 mg
£541,00
30-1241-0.1MG
Über dieses Produkt
- SKU:
- 30-1241
- Zusätzliche Namen:
- CD33||SIGLEC3
- translate.label.attr.clone:
- HIM3-4
- Klonalität:
- Monoclonal
- Weitere Details:
- CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage; binds sialic acid residues in N- and O-glycans on cell surfaces; and is a therapeutic target for acute myeloid leukemia.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- NFMY-9s human cell line
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- Purified by protein-A affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php