Anti-CD95 / Fas Monoclonal Antibody (Clone:LT95)
Produktgrößen
0.1 mg
£532,00
30-1238-0.1MG
Über dieses Produkt
- SKU:
- 30-1238
- Zusätzliche Namen:
- Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediating surface antigen FAS
- translate.label.attr.clone:
- LT95
- Klonalität:
- Monoclonal
- Weitere Details:
- CD95 (Fas; APO-1); a 46 kDa transmembrane glycoprotein; is a cell death receptor of the TNFR superfamily. Stimulation of CD95 results in aggregation of its intracellular death domains; formation of the death-inducing signaling complex (DISC) and activation of caspases. In type I cells caspase 3 is activated by high amounts of caspase 8 generated at the DISC; in type II cells low concentration of caspase 8 activates pathway leading to the release of cytochrome c from mitochondria and activation of caspase 3 by cytochom c. Besides its roles in induction of apoptosis; Fas also triggers pro-inflammatory cytokine responses.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- HUT-78 human T cell lymphoma cell line
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- Purified by protein-A affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php