Anti-CD71 / Transferrin Receptor Monoclonal Antibody (Clone:MEM-189)
Produktgrößen
0.1 mg
£532,00
30-1230-0.1MG
Über dieses Produkt
- SKU:
- 30-1230
- Zusätzliche Namen:
- TFRC
- translate.label.attr.clone:
- MEM-189
- Klonalität:
- Monoclonal
- Weitere Details:
- CD71 (transferrin receptor) is a type II transmembrane glycoprotein expressed as homodimer in erythroid blood cell line and in activated leukocytes. Upon binding of holotransferrin (complex of transferrin and iron ions); CD71 is internalized by clathrin-mediated endocytosis. Acidification of endosomes by vesicular membrane proton pumps leads to dissociation of iron ions; whereas transferrin (apotransferrin) remains associated with CD71 and recycles to the cell surface; where it is released upon exposure to normal pH. CD71 is also involved in uptake of non-transferrin bound iron.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- KG1 human acute myelogenous leukaemia cell line
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- Purified by protein-A affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php