Anti-NHERF1 / EBP50 Monoclonal Antibody (Clone:EBP-10)
Produktgrößen
0.1 mg
£581,00
30-1226-0.1MG
Über dieses Produkt
- SKU:
- 30-1226
- Zusätzliche Namen:
- SLC9A3R1||NHERF||NHERF1
- translate.label.attr.clone:
- EBP-10
- Klonalität:
- Monoclonal
- Weitere Details:
- NHERF1 (Na+/H+ exchanger regulatory factor 1); also known as EBP50 (ezrin; radixin; moesin-binding phosphoprotein 50) is an adaptor protein; which associates with beta-catenin and is required for its localization at the cell-cell junctions; interacts with various G protein-coupled receptors and regulates their traffic; as well as sodium-hydrogen exchange and sodium-dependent phosphate transport. NHERF1/EBP50 inhibits cell motility and is required to suppress anchorage-independent growth. It contains C-terminal ERM (ezrin; radixin; moesin)-binding region and two N-terminal PDZ (postsynaptic-density-95/disc-large/ZO1 homology) domains and is able to form head-to-tail intramolecular conformation to regulate its interactions.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Bacterially produced recombinant full-length human NHERF1.
- Isotyp:
- Mouse IgG2b
- Aufreinigung:
- Purified by protein-A affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php