Anti-CD27 Monoclonal Antibody (Clone:LT27)
Produktgrößen
0.1 mg
£532,00
30-1195-0.1MG
Über dieses Produkt
- SKU:
- 30-1195
- Zusätzliche Namen:
- CD27||TNFRSF7
- translate.label.attr.clone:
- LT27
- Klonalität:
- Monoclonal
- Weitere Details:
- CD27 is a transmembrane 55 kDa protein of the nerve growth factor-receptor family; expressed as a disulfide-linked homodimer on mature thymocytes; peripheral blood T cells and a subpopulation of B cells. Activation of T cells via TCR-CD3 complex results in upregulation of CD27 expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form; sCD27; detected in the plasma; urine or spinal fluid. This sCD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA; a cystein proteinase; although activating T cells through the protease-activated receptors (PARs); degradates CD27 and counteracts T cell activation mediated by CD27 and its ligand CD70.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Human peripheral blood lymphocytes
- Isotyp:
- Mouse IgG2a
- Aufreinigung:
- Purified by precipitation and chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php