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Antikörper

Anti-CD53 Monoclonal Antibody (Clone:MEM-53)

Produktgrößen
0.1 mg
£532,00
30-1132-0.1MG
Über dieses Produkt
SKU:
30-1132
Zusätzliche Namen:
CD53||MOX44||TSPAN25
translate.label.attr.clone:
MEM-53
Klonalität:
Monoclonal
Weitere Details:
CD53 is a tetraspanin family transmembrane glycoprotein expressed in the lymphoid-myeloid lineage. This molecule has been reported to form complexes with other leukocyte surface proteins such as CD2; CD19; CD21; MHC II; VLA-4 or tetraspanins CD37; CD81 and CD82; thus probably modulating various signaling processes. CD53 is involved in radioresistancy of tumour cells and its triggering has anti-apoptotic effect. In thymus; CD53 is up-regulated in response to positive selection signals during T cell development; and is strongly expressed upon macrophage exposure to bacterial lipopolysaccharide; whereas stimulation of neutrophils results in down-regulation of CD53 expression.
Format:
Purified
Host:
Mouse
Immunogen:
Leukocytes of pacient suffering from a LGL-type leukemia.
Isotyp:
Mouse IgG1
Aufreinigung:
Purified by protein-A affinity chromatography
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at 2-8[o]C. Do not freeze.
Hersteller:
Abeomics
Typ:
Antibodies:Monoclonal Antibody