Anti-CD45RB Monoclonal Antibody (Clone:MEM-55)
Produktgrößen
0.1 mg
£532,00
30-1129-0.1MG
Über dieses Produkt
- SKU:
- 30-1129
- translate.label.attr.clone:
- MEM-55
- Klonalität:
- Monoclonal
- Weitere Details:
- CD45RB is an of a receptor-type protein tyrosine phosphatase; CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling; serving as an important regulator of Src-family kinases; promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains; whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45RB is expressed e.g. in microglia and inflammatory cells.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Human thymocytes and T lymphocytes.
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- Purified by protein-A affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:1.jpg