Anti-CD6 Monoclonal Antibody (Clone:MEM-98)
Produktgrößen
0.1 mg
£532,00
30-1111-0.1MG
Über dieses Produkt
- SKU:
- 30-1111
- Zusätzliche Namen:
- CD6
- translate.label.attr.clone:
- MEM-98
- Klonalität:
- Monoclonal
- Weitere Details:
- CD6; also known as T12; is a member of the scavenger receptor superfamily found on T and B cell subsets; thymocytes; and acute lymphocytic leukemia cells (ALL). CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse. CD6-ALCAM mediated cell adhesion is also important for T cell proliferation. CD6 may exert some its functions via association with CD5; probably by fine-tuning CD5 signaling. Ligation of CD6 has antiapoptotic role in chronic lymphocytic leukemia B cells.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Human CD6 antigen purified by immunoaffinity chromatography from HBP-ALL cells followed by preparative SDS-PAGE of non-boiled non-reduced sample (excised piece of gel corresponding to the 100 kDa zone).
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- Purified by protein-A affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php