Anti-CD193 / CCR3 Monoclonal Antibody (Clone:5E8) PE-Cy™5 conjugated
Produktgrößen
100TESTS
£724,00
30-1080PE-Cy5-100TESTS
Über dieses Produkt
- SKU:
- 30-1080PE-Cy5
- Zusätzliche Namen:
- CCR3||CMKBR3||CKR3||CKR-3
- translate.label.attr.clone:
- 5 E 8
- Klonalität:
- Monoclonal
- Konjugat:
- PE
- Weitere Details:
- Specificity: The mouse monoclonal antibody 5E8 recognizes an extracellular epitope of CD193 (chemokine receptor 3); an approximately 41 kDa protein expressed above all in eosinophils and basophils. Description: CD193 / CCR3 is a G-protein coupled receptor for several chemokines; namely CCL11 (eotaxin); CCL26 (eotaxin-3); CCL7 (MCP-4); or CCL5 (RANTES). It is highly expressed on eosinophils and basophils; and is also detected in TH1 and TH2 cells; as well as in airway epithelial cells. CD193 is the key eosinophil chemokine receptor responsible for regulation of eosinophil migration and function. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1.
- Host:
- Mouse
- Immunogen:
- human CD193 transfectants
- Isotyp:
- Mouse IgG2b kappa
- Aufreinigung:
- Purified antibody is conjugated with activated tandem dye of R-phycoerythrin-cyanine 5 (PE-Cy™5) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:img1.jpg
