Anti-CD89 Monoclonal Antibody (Clone:A59)
Produktgrößen
0.1 mg
£532,00
30-1063-0.1MG
Über dieses Produkt
- SKU:
- 30-1063
- Zusätzliche Namen:
- FCAR; CD89; IgA Fc receptor
- translate.label.attr.clone:
- A59
- Klonalität:
- Monoclonal
- Weitere Details:
- CD89 (Fc-alpha-R) is a type I transmembrane glycoprotein serving as a receptor for IgA. Soluble CD89 is detectable in serum and retains its IgA binding capacity. For signal transduction the association with FcR gamma chain homodimers is needed. CD89 is expressed on granulocytes; monocytes; macrophages; dendritic cells and myeloid cell lines. Its expression is upregulated in presence of IgA immune complexes; stimulators (such as LPS; PMA); TNF alpha; IL1 beta or GM-CSF; and it is downregulated in presence of TGF beta and suramin. Binding of IgA-opsonized targets to CD89 leads to phagocytic and cytotoxic processes of the immunologic defense.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Ag8.653 myeloma cells
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- Purified by protein-A affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php