Anti-CD22 / BL-CAM Monoclonal Antibody (Clone:IS7)-Azide free
Produktgrößen
0.1 mg
£570,00
30-1022-0.1MG
Über dieses Produkt
- SKU:
- 30-1022
- Zusätzliche Namen:
- CD22||SIGLEC2
- translate.label.attr.clone:
- IS7
- Klonalität:
- Monoclonal
- Weitere Details:
- CD22; also known as Siglec-2 (sialic acid-binding immunoglobulin-like lectin-2) is a transmembrane glycoprotein binding alpha2;6-linked sialic acid-bearing ligands. Intracellular domain of CD22 recruits protein tyrosine phosphatase SHP-1 through the immunoreceptor tyrosine-based inhibitory motifs (ITIMs); thus setting a treshold for B cell receptor-mediated activation. CD22 also regulates B-cell response by involvement in controlling the CD19/CD21-Src-family protein tyrosine kinase amplification pathway and CD40 signaling. CD22 exhibits hallmarks of clathrin-mediated endocytic pathway.
- Format:
- Azide free
- Host:
- Mouse
- Immunogen:
- human cell line Reh
- Isotyp:
- Mouse IgG1
- Aufreinigung:
- Purified by protein-A affinity chromatography
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:download_pdf.php