Anti-CD54 / ICAM-1 Monoclonal Antibody (Clone:1H4) PE-Cy™7 conjugated
Produktgrößen
100TESTS
£760,00
30-1018PE-Cy7-100TESTS
Über dieses Produkt
- SKU:
- 30-1018PE-Cy7
- Zusätzliche Namen:
- ICAM1;ICAM-1; BB2; P3.58
- translate.label.attr.clone:
- 1H4
- Klonalität:
- Monoclonal
- Konjugat:
- PE/CY7
- Weitere Details:
- Specificity: The antibody 1H4 recognizes an extracellular epitope of CD54 (ICAM-1); a 85-110 kDa type I transmembrane glycoprotein (receptor for rhinovirus) expressed on activated endothelial cells; T lymphocytes; B lymphocytes; monocytes; macrophages; granulocytes and dendritic cells; the expression of CD54 is upregulated by activation. Description: CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites; expressed on resting monocytes and endothelial cells and can be upregulated on many other cells; e.g. with lymphokines; on B- and T-lymphocytes; thymocytes; dendritic cells and also on keratinocytes; chondrocytes; as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation.
- Host:
- Mouse
- Immunogen:
- Raji cells and spleen cells fused with NS1 cells
- Isotyp:
- Mouse IgG2b
- Aufreinigung:
- Purified antibody is conjugated with activated tandem dye of R-phycoerythrin-cyanine 7 (PE-Cy™7) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 2-8[o]C. Do not freeze.
- Hersteller:
- Abeomics
- Typ:
- Antibodies:Monoclonal Antibody
- Datenblatt des Herstellers:img1.jpg
