Human PD-L1 Recombinant Fc fusion Protein (Active) Biotin conjugated
Produktgrößen
100µg
£551,00
21-1001-B-100UG
Über dieses Produkt
- SKU:
- 21-1001-B
- Zusätzliche Namen:
- B7 homolog 1; CD274; B7H1; PDCD1L1; PDCD1LG1; PDL1
- Weitere Details:
- Host: CHO-K1 celline. PD-L1 (CD274/B7-H1) is a critical membrane-bound costimulatory molecule belongs to the B7 superfamily that inhibits immune responses through its receptor; PD-1 and PD-L1 play a key role in the pathogenesis of inflammatory diseases (programmed death 1). It is widely expressed in the mononuclear phagocyte system (MPS); may co-stimulate T cells and regulates inflammatory responses. PD-L1 exerts inflammation regulatory functions via a negative co-stimulatory effect on T cell functions to inhibit cytokine secretion; facilitate apoptosis of activated T cells and induce T cell anergy. Aberrant expression and dysregulation of CD274 have been reported during bacterial infection; inflammation and in numerous autoimmune diseases.
- Aufreinigung:
- 99% Purity SDS -PAGE and HPLC.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store it under sterile conditions at -4[o]C. It is recommended that the protein be aliquoted for optimal storage.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg
