E-64d
Produktgrößen
1 mg
£210,00
15-4009-1MG
5 mg
£408,00
15-4009-5MG
Über dieses Produkt
- SKU:
- 15-4009
- Zusätzliche Namen:
- Aloxistatin; E-64c ethyl ester;EP 453; EST; Loxistatin; NSC 694281
- Weitere Details:
- Molecular Formula: C17H30N2O5 Molecular Weight: 342.4 Cysteine proteases are a class of enzymes containing an active-site cysteine residue that is important in protein degradation pathways. E-64d; a synthetic analog of E-64 and ethyl ester of E-64c; is an irreversible; membrane-permeable inhibitor of lysosomal and cytosolic cysteine proteases.E-64d inhibits calpain and the cysteine proteases cathepsins F; K; B; H; and L. By disrupting protease activity; E-64d; at concentrations between 20-200 µM; has been shown to arrest human epidermoid carcinoma A431 cells at mitotic metaphase.It also inhibits protease-resistant prion protein accumulation in scrapie-infected neuroblastoma cells with an IC50 value of 0.5 µM.
- Aufreinigung:
- >=98%
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20[o]C; product is stable for at least two years.
- Hersteller:
- Abeomics
- Typ:
- Biomaterials
- Datenblatt des Herstellers:1.png