Grazoprevir
Produktgrößen
5 mg
£243,00
15-4003-5MG
10 mg
£386,00
15-4003-10MG
Über dieses Produkt
- SKU:
- 15-4003
- Zusätzliche Namen:
- MK-5172
- Weitere Details:
- Molecular Formula: C38H50N6O9S Molecular Weight: 766.9 Grazoprevir is a pan-genotypic protease inhibitor that binds to hepatitis C virus (HCV) non-structural protein 3/4A (NS3/4A); a serine protease essential for viral replication.Grazoprevir has potent in vitro activity against major HCV genotypes (Kis = 0.1; 0.1; 0.08; 0.15; and 0.9 nM for genotypes 1a; 1b; 2a; 2b; and 3a; respectively) and common resistance genotypes (Kis = 0.07; 0.14; and 0.30 nM for genotypes 1b R155K; D165V; and D168Y; respectively). Grazoprevir inhibits the NS3/4A protease in an in vitro replicon system with EC50 values of 2 and 8 nM for genotypes 1a and 2a; respectively. Formulations containing grazoprevir are used in combination therapies to treat HCV.
- Aufreinigung:
- >=98%
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20[o]C.
- Hersteller:
- Abeomics
- Typ:
- Biomaterials
- Datenblatt des Herstellers:1.png