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TLR5/HEK293 Stable Cell Line

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1 Vial
£2747,00
14-534ACL-1VIAL
Über dieses Produkt
SKU:
14-534ACL
Weitere Details:
TLR5/HEK293 Stable Cell Line is a stably transfected HEK293 cell line which expresses human Toll-like receptor 5 (TLR5; also designated as CD285). TLR5 mediates immune responses by recognition of bacterial flagellin; of which activation involves in various human diseases including inflammatory bowel disease; rheumatoid arthritis; osteoclastogenesis; gastric cancer; cervical cancer and ovarian cancer. Note that TLR5 in the TLR5/HEK293 stable cell line contains the N-terminal HA tag (Figure 2); which does not interfere with TLR5 activity as confirmed by functional assay (Figure 1). Sequence data: Human TLR5 (accession number NP_003259) MGDHLDLLLGVVLMAGPVFGIPSCSFDGRIAFYRFCNLTQVPQV LNTTERLLLSFNYIRTVTASSFPFLEQLQLLELGSQYTPLTIDKEAFRNLPNLRILDL GSSKIYFLHPDAFQGLFHLFELRLYFCGLSDAVLKDGYFRNLKALTRLDLSKNQIRSL YLHPSFGKLNSLKSIDFSSNQIFLVCEHELEPLQGKTLSFFSLAANSLYSRVSVDWGK CMNPFRNMVLEILDVSGNGWTVDITGNFSNAISKSQAFSLILAHHIMGAGFGFHNIKD PDQNTFAGLARSSVRHLDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAFYG LDNLQVLNLSYNLLGELYSSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLQTLDLR DNALTTIHFIPSIPDIFLSGNKLVTLPKINLTANLIHLSENRLENLDILYFLLRVPHL QILILNQNRFSSCSGDQTPSENPSLEQLFLGENMLQLAWETELCWDVFEGLSHLQVLY LNHNYLNSLPPGVFSHLTALRGLSLNSNRLTVLSHNDLPANLEILDISRNQLLAPNPD VFVSLSVLDITHNKFICECELSTFINWLNHTNVTIAGPPADIYCVYPDSFSGVSLFSL STEGCDEEEVLKSLKFSLFIVCTVTLTLFLMTILTVTKFRGFCFICYKTAQRLVFKDH PQGTEPDMYKYDAYLCFSSKDFTWVQNALLKHLDTQYSDQNRFNLCFEERDFVPGENR IANIQDAIWNSRKIVCLVSRHFLRDGWCLEAFSYAQGRCLSDLNSALIMVVVGSLSQY QLMKHQSIRGFVQKQQYLRWPEDLQDVGWFLHKLSQQILKKEKEKKKDNNIPLQTVAT IS
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Immediately upon receipt; store in liquid nitrogen.
Hersteller:
Abeomics
Typ:
Cells:Cell Lines
Fig-2: Western blot analysis of TLR5 expression in the TLR5/HEK293 cell line. Cell lysates were analyzed by SDS-PAGE followed by Western blotting using anti-HA antibody. Note that TLR5 in the TLR5/HEK293 stable cell line contains the N-terminal HA tag. Control; parental HEK293 cell lysate; TLR5; TLR5/HEK293 cell lysate.
Fig-2: Western blot analysis of TLR5 expression in the TLR5/HEK293 cell line. Cell lysates were analyzed by SDS-PAGE followed by Western blotting using anti-HA antibody. Note that TLR5 in the TLR5/HEK293 stable cell line contains the N-terminal HA tag. Control; parental HEK293 cell lysate; TLR5; TLR5/HEK293 cell lysate.