STAT3 Leeporter™ Luciferase Reporter-HEK293 Cell Line
Produktgrößen
1 Vial
£4481,00
14-114ACL-1VIAL
Über dieses Produkt
- SKU:
- 14-114ACL
- Weitere Details:
- The STAT3 Leeporter™ Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses Renilla luciferase reporter under the transcriptional control of the STAT3 responsive promoter; so that the cell line is designed to measure the transcriptional activity of STAT3. As a transcription factor; Signal Transducer and Activator of Transcription 3 (STAT3) is activated through phosphorylation at tyrosine 705 in response to various cytokines including IL-6; interferons; epidermal growth factor; hepatocyte growth factor and leukemia inhibitory factor. The phosphorylated STAT3 forms homodimers or heterodimers with STAT1; and the dimers translocate to nucleus in which DNA binding/promoter induction occurs. The STAT3 induction by IL-6 as well as Oncostatin-M is shown in Figures 1 and 3.
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- Immediately upon receipt; store in liquid nitrogen.
- Hersteller:
- Abeomics
- Typ:
- Cells:Cell Lines
- Datenblatt des Herstellers:14-114ACL_STAT3_HEK293_Fig1new.png
